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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYST2
All Species:
18.18
Human Site:
S226
Identified Species:
28.57
UniProt:
O95251
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95251
NP_008998.1
611
70642
S226
E
C
K
V
R
A
Q
S
R
D
K
Q
I
E
E
Chimpanzee
Pan troglodytes
XP_511869
806
91579
S421
E
C
K
V
R
A
Q
S
R
D
K
Q
I
E
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548192
555
64081
N187
L
S
H
R
Q
D
D
N
N
R
H
A
T
R
H
Cat
Felis silvestris
Mouse
Mus musculus
Q5SVQ0
613
70623
S228
E
C
K
V
R
A
Q
S
R
D
K
Q
I
E
E
Rat
Rattus norvegicus
Q810T5
612
70496
S227
E
C
K
V
R
A
Q
S
R
D
K
Q
I
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026512
611
70527
S226
E
C
K
V
R
A
Q
S
R
D
K
Q
I
E
E
Frog
Xenopus laevis
NP_001079995
617
71123
F226
E
C
K
N
C
D
E
F
Q
V
R
A
Q
S
R
Zebra Danio
Brachydanio rerio
NP_997800
568
65560
E200
E
R
S
Q
G
Q
N
E
E
N
R
H
A
T
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q960X4
541
61216
R173
L
A
A
A
L
Q
K
R
I
N
R
K
R
K
N
Honey Bee
Apis mellifera
XP_392324
916
101344
R518
C
A
E
F
Y
K
E
R
K
K
R
E
E
D
R
Nematode Worm
Caenorhab. elegans
Q9TYU5
458
53125
E90
R
L
N
L
A
S
C
E
L
P
K
K
G
G
K
Sea Urchin
Strong. purpuratus
XP_782361
504
58083
K136
S
T
G
K
G
D
A
K
L
T
N
G
E
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXD7
445
51348
P77
W
R
D
G
K
H
H
P
V
K
V
I
E
R
R
Baker's Yeast
Sacchar. cerevisiae
Q08649
445
52594
E77
D
R
I
N
L
D
K
E
V
L
Y
P
K
L
K
Red Bread Mold
Neurospora crassa
Q7S9B6
506
58788
E138
Q
T
P
H
P
W
T
E
F
V
E
S
Q
P
G
Conservation
Percent
Protein Identity:
100
75.8
N.A.
89.3
N.A.
99
99
N.A.
N.A.
97.8
93.1
76.4
N.A.
33.7
34
30.9
39.2
Protein Similarity:
100
75.8
N.A.
89.5
N.A.
99
99
N.A.
N.A.
98.5
95.9
83.4
N.A.
49.5
48.1
48.6
53.8
P-Site Identity:
100
100
N.A.
0
N.A.
100
100
N.A.
N.A.
100
20
6.6
N.A.
0
0
6.6
0
P-Site Similarity:
100
100
N.A.
13.3
N.A.
100
100
N.A.
N.A.
100
40
20
N.A.
33.3
40
33.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.3
31.9
31.2
Protein Similarity:
N.A.
N.A.
N.A.
50.4
47.6
47.4
P-Site Identity:
N.A.
N.A.
N.A.
0
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
7
7
7
34
7
0
0
0
0
14
7
0
0
% A
% Cys:
7
40
0
0
7
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
7
0
0
27
7
0
0
34
0
0
0
7
0
% D
% Glu:
47
0
7
0
0
0
14
27
7
0
7
7
20
34
34
% E
% Phe:
0
0
0
7
0
0
0
7
7
0
0
0
0
0
0
% F
% Gly:
0
0
7
7
14
0
0
0
0
0
0
7
7
7
7
% G
% His:
0
0
7
7
0
7
7
0
0
0
7
7
0
0
7
% H
% Ile:
0
0
7
0
0
0
0
0
7
0
0
7
34
0
0
% I
% Lys:
0
0
40
7
7
7
14
7
7
14
40
14
7
7
14
% K
% Leu:
14
7
0
7
14
0
0
0
14
7
0
0
0
14
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
14
0
0
7
7
7
14
7
0
0
0
7
% N
% Pro:
0
0
7
0
7
0
0
7
0
7
0
7
0
7
0
% P
% Gln:
7
0
0
7
7
14
34
0
7
0
0
34
14
0
0
% Q
% Arg:
7
20
0
7
34
0
0
14
34
7
27
0
7
14
27
% R
% Ser:
7
7
7
0
0
7
0
34
0
0
0
7
0
7
7
% S
% Thr:
0
14
0
0
0
0
7
0
0
7
0
0
7
7
0
% T
% Val:
0
0
0
34
0
0
0
0
14
14
7
0
0
0
0
% V
% Trp:
7
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
0
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _